Merck KGaA Investor Presentation — September 2017

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Stefan Oschmann, CEO

Munich , September 18, 2017MERCK KGAA ,

DARMSTADT, GERMANY –

SIXTH GERMAN CORPORATE CONFERENCE2Disclaimer

Publication ofMerck KGaA ,Darmstadt, Germany .IntheUnited States andCanada

thegroup ofcompanies affiliated withMerck KGaA ,Darmstadt, Germany operates

under individual business names (EMD Serono, Millipore Sigma, EMD Performance

Materials) .Toreflect such factandtoavoid anymisconceptions ofthereader ofthe

publication certain logos, terms andbusiness descriptions ofthepublication have

been substituted oradditional descriptions have been added .Thisversion ofthe

publication, therefore, slightly deviates from theotherwise identical version ofthe

publication provided outside theUnited States andCanada .

Cautionary Note Regarding Forward -Looking Statements andfinancial indicators

Thiscommunication may include “forward -looking statements .”Statements thatinclude words such as“anticipate,” “expect,” “should,” “would,” “intend,” “plan,” “project,” “seek,”

“believe,” “will,” andother words ofsimilar meaning inconnection withfuture events orfuture operating orfinancial performance areoften used toidentify forward -looking statements .

Allstatements inthiscommunication, other than those relating tohistorical information orcurrent conditions, areforward -looking statements .Weintend these forward -looking

statements tobecovered bythesafeharbor provisions forforward -looking statements inthePrivate Securities Litigation Reform Actof1995.These forward -looking statements are

subject toanumber ofrisks anduncertainties, many ofwhich arebeyond control ofMerck KGaA ,Darmstadt, Germany, which could cause actual results todiffer materially from such